抗性淀粉影响帕金森病可能作用机制的研究进展OA

Parkinson's disease(PD)is the second largest neurodegenerative disease,and it has become one of the central nervous system diseases that pose a major social problem and economic threat.However,because its pathogenesis is not completely clear,there is a lack of drugs to prevent the development of the disease and cure PD in clinic.With people's increasing attention to health,a brand-new diet therapy is being constructed,which is based on increasing the intake of resistant starch(RS),thus changing the intestinal microflora,leading to the increase of short-chain fatty acids produced by microorganisms and stimulating intestinal cells to secrete glucagon-like peptide-1(GLP-1).The possible function mechanism of RS is comprehensively expounded in improving PD symptoms in this paper,and its application prospect is envisioned in the prevention and treatment of PD in the future.