以水杨酸为碳源,碳酸铵为氮源,通过一步水热法合成一种在 365 nm紫外光下发蓝色荧光的水溶性氮掺杂碳量子点(N-CQDs).该量子点的荧光量子产率达 19.8%,透射电镜(TEM)显示其形貌接近圆球形,平均粒径约为 7.2 nm.利用 X射线电子衍射仪(XRD)、傅里叶变换红外分光光度计(FTIR)、紫外分光光度计、荧光分光光度计分别对其结构和性质进行表征.实验发现,阿司匹林(ASA)对 N-CQDs的荧光有增敏作用.基于此建立了一种快速检测阿司匹林的定量方法,其线性范围为 0～80 μmol/L,检出限为 0.046 μmol/L.将该荧光传感器用于实际样品检测,回收率为 95.3%～105.2%.
Using salicylic acid as carbon source and ammonium carbonate as nitrogen source,a water-soluble nitrogen-doped carbon quantum dots(N-CQDs)with blue fluorescence under 365 nm ultraviolet light were synthesized by a one-step hydrothermal method.The fluorescence quantum yield of the N-CQDs was 19.8%.Transmission electron microscopy(TEM)showed that the morphology of the N-CQDs was nearly spherical,and the average particle size was about 7.2 nm.X-ray electron diffractometer(XRD),Fourier transform infrared spectrophotometer(FTIR),ultraviolet spectrophotometer and fluorescence spectrophotometer were used to characterize the structure and properties of the composite.The experiment found that aspirin(ASA)had a sensitizing effect on the fluorescence of N-CQDs.Based on this,a rapid quantitative method for aspirin detection was established.The linear range was 0-80 μmol/L,and the detection limit was 0.046 μmol/L.The recovery rate was 95.3%-105.2%when the fluorescent sensor was applied to real samples.
卜晓阳;李萍;周思了;陈云艳
皖南医学院药学院,安徽 芜湖 241002
化学
氮掺杂碳点;阿司匹林;荧光增强
nitrogen-doped carbon dots;aspirin;fluorescence enhancement
《杭州师范大学学报（自然科学版）》 2024 (004)
388-394 / 7
安徽省自然科学基金项目(2108085QH370);皖南医学院中青年科研基金项目(wk202008);2023年度国家科学中心大健康研究院新安医学与中医药现代化研究所"揭榜挂帅"项目(2023CXMMTCM023).
10.19926/j.cnki.issn.1674-232X.2024.01.042
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