分次手术切除巨大汗孔角化症1例OA

To report a case of staged surgical excision of giant porokeratosis.A 54-year-old man had been seeking medical attention for 29 years due to an itchy purplish-red spot on the right upper abdomen.Dermatological examination revealed a well-defined round purplish-red patch,ap-proximately 15 cm x 15 cm,with rough keratinization and few attached scales on the surface.Brown color was observed around the lesion without any noticeable elevation,erosion or exudation.Histopathological analysis showed hyperkeratosis and parakeratosis,loss of granular layers,irregu-lar thickening of the stratum spinosum,superficial dermal vasodilation and perivascular infiltration of mononucleated cells along with melanophages.Dermoscopy revealed dark red background with clear boundaries,whitish peripheral rim and linear vessels,focal hypopigmentation,comma-like vessels at center,as well as thickened yellow scales in the surrounding area.Diagnosis was poro-keratosis of Mibelli.The skin lesion was surgically removed using a staged excision method over four stages,resulting in successful healing without recurrence during one-year follow-up.