目的:探讨嗓音中医开喉亮音法治疗新型冠状病毒感染后单侧声带麻痹的临床疗效.方法:将 29 例新型冠状病毒感染后单侧声带麻痹患者按照随机数字表法分为对照组(14 例)和研究组(15 例).对照组给予甲钴胺片口服,研究组给予嗓音中医开喉亮音法.比较两组患者治疗前后的主观听感知评估量表(GRBAS)评分、嗓音障碍指数(voice handicap index,VHI)量表评分、嗓音声学指标与气流动力学指标及两组临床疗效.结果:(1)研究组有效率为 93.33%(14/15),对照组为 57.14%(8/14),两组有效率比较,差异有统计学意义(P<0.05).(2)研究组治疗后GRBAS评分[总嘶哑度(0.79±0.43)分、粗糙声(0.55±0.32)分和气息声(0.25±0.15)分]明显低于同期对照组(P<0.05).(3)研究组治疗后VHI评分[功能(6.74±1.43)分、生理(12.87±2.86)分和情感(5.88±1.11)分]明显低于同期对照组(P<0.05).(4)研究组治疗后嗓音声学指标[基频(166.58±23.44)Hz、基频微扰(1.89±0.84)%和振幅微扰(2.18±0.79)%]明显低于同期对照组(P<0.05).(5)研究组治疗后气流动力学[最长发音时间(13.36±3.07)s、最大发音时间(13.27±3.14)s]均长于同期对照组,气流率[(100.75±20.14)mL·s-1]明显低于同期对照组(P<0.05).结论:嗓音中医开喉亮音法治疗新型冠状病毒感染后单侧声带麻痹疗效显著,能有效改善患者声音嘶哑程度,改善发声功能和嗓音功能,提高嗓音质量.
Objective:To explore the clinical efficacy of voice opening and bright voice method of traditional Chinese medicine in the treatment of unilateral vocal cord paralysis after COVID-2019 infection.Methods:29 patients with unilateral vocal cord paralysis after COVID-2019 infection were randomly divided into control group(14 cases)and study group(15 cases).The control group was given oral methylcobalamin tablets,while the study group was given the traditional Chinese medicine method of opening the throat and brighte-ning the voice.Compare the subjective auditory perception assessment scale(GRBAS)scores,voice impairment index(VHI)scores,voice acoustic and aerodynamic indicators,and clinical efficacy between two groups of patients before and after treatment.Result:(1)The effective rate of the study group was 93.33%(14/15),while that of the control group was 57.14%(8/14).The difference in ef-fective rates between the two groups was statistically significant(P<0.05).(2)The GRBAS score[total hoarseness score(0.79±0.43),roughness score(0.55±0.32),and breath score(0.25±0.15)]in the study group after treatment were significantly lower than those in the control group during the same period(P<0.05).(3)The VHI scores[functional(6.74±1.43),physiological(12.87±2.86),and emotional(5.88±1.11)]of the study group after treatment were significantly lower than those of the control group during the same period(P<0.05).(4)After treatment,the acoustic indicators of the voice in the study group[fundamental fre-quency(166.58±23.44)Hz,fundamental frequency perturbation(1.89±0.84)%,and amplitude perturbation(2.18±0.79)%]were significantly lower than those in the control group during the same period(P<0.05).(5)Aftertreatment,theairflowdynamicsof the study group[longest pronunciationtime(13.36±3.07)s,maximum pronunciation time(13.27±3.14)s]were longer than those of the control group during the same period,and the airflow rate[(100.75±20.14)mL·s-1]was significantly lower than that of the control group during the same period(P<0.05).Conclusion:The TCM method of opening throat and brightening voice is effec-tive in the treatment of unilateral vocal cord paralysis after COVID-2019 infection,which can effectively improve the hoarseness degree of patients,voice production function and voice function,and voice quality.
赵丹丹;贾丽;李元钦;梅祥胜;尚艳华;王冰;刘媛媛;许冬玉;马潇遥;王瑞雪;熊丹丹
河南中医药大学第一附属医院,河南 郑州 450000
中医学
单侧声带麻痹;嗓音中医开喉亮音法;新型冠状病毒;声音嘶哑;嗓音障碍
unilateral vocal cord paralysis;TCM method of opening throat and brightening voice;COVID-2019;hoarse voice;voice disorder
《中医学报》 2024 (006)
1337-1343 / 7
河南省中医药科学研究专项基金项目(2022ZY1041,2023ZY2017)
10.16368/j.issn.1674-8999.2024.06.223
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