Hepatoid adenocarcinoma of the stomach (HAS) is a rare malignant gastric tumor exhibiting both hepatocellular and adenocarcinomatous differentiation. Patients are often diagnosed at an advanced stage, and their clinical symptoms closely resemble those of gastric adeno-carcinoma. Because of its rarity, misdiagnosis and missed diagnoses are prevalent. Compared with gastric adenocarcinoma, HAS typi-cally exhibits higher invasiveness and a more unfavorable prognosis. This review aimed to elaborate on the pathological features, potential mechanisms, clinical characteristics, diagnosis, and prognosis of HAS. The insights provided aimed to contribute robust guidance for the clinical management of patients with HAS.
Kai Qin;Jing Zhang;Chen Gong;Yi Cheng
Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
Diagnosis;Hepatoid adenocarcinoma of the stomach;Progress
《肿瘤学与转化医学(英文)》 2024 (002)
54-59 / 6
This study was supported by the Natural Science Foundation of Hubei Province(no.2020CFB592).
10.1097/ot9.0000000000000035
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