Gonadal soma-derived factor(Gsdf)is a member of the transforming growth factor beta(TGF-β)superfamily and a teleost-specific gene.Early studies suggested that Gsdf promotes spermatogonial proliferation;however recent reports have shed light on its role in sex differentiation based on expression profiles and gain-and loss-of-function studies.This paper discusses the involvement of Gsdf in gonadal sex differentiation and sex changes in teleosts.
Tohru Kobayashi
Laboratory of Molecular Reproductive Biology,Institute for Environmental Sciences,University of Shizuoka,Shizuoka,422-8526,Japan||Graduate School of Pharmaceutical and Nutritional Sciences,University of Shizuoka,Shizuoka,422-8526,Japan
Teleosts;Medaka;Gsdf;Sex determination;Sex differentiation;Sex change;Pituitary
《渔业学报（英文）》 2024 (003)
417-421 / 5
This work was supported by UK-Japan Research Collaboration Grants from the Ministry of the Environment,Japan,and JSPS KAKENHI grant No.18H02281 awarded to T.K.
10.1016/j.aaf.2023.04.002
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