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术中监测局部脑氧饱和度在老年直肠癌根治术患者POD中的预测价值OA

The predictive value of intraoperative monitoring of regional cerebral oxygen saturation in POD in elderly patients undergoing radical resection of rectal cancer

中文摘要英文摘要

的探讨术中监测局部脑氧饱和度(rSO2)在老年直肠癌根治术患者术后谵妄(POD)中的预测价值.方法 选取2022年8月至2023年2月在甘肃省人民医院麻醉科行直肠癌根治术的88例老年患者为研究对象,入室后监测麻醉诱导前(T0)、气管插管后(T1)、手术开始时(T2)、手术开始1 h(T3)、手术开始2 h(T4)和手术结束(T5)rSO2、心率(HR)、平均动脉压(MAP)、血氧饱和度(SpO2),以T0时rSO2为基线值,计算rSO2最小值(rSO2 min)、平均值(rSO2 mean)、与基线值下降的最大差值(rSO2%max).术后根据是否出现POD分为POD组和非POD组,比较两组HR、MAP、SpO2及rSO2.结果 POD组和非POD组T0、T1、T2、T3、T4和T5时HR、MAP、SpO2以及T0、T1、T2时rSO2指标比较,差异无统计学意义(P>0.05),POD组T3、T4和T5时rSO2低于非POD组,差异有统计学意义(P<0.05).POD组与非POD组rSO2基线值比较,差异无统计学意义(P>0.05),POD组rSO2 min和rSO2 mean低于非POD组,POD组rSO2%max高于非POD组,差异有统计学意义(P<0.05).结论 rSO2降低与老年直肠癌根治术患者POD相关,可将rSO2作为预测POD的指标.

Objective To explore the predictive value of intraoperative monitoring of regional cerebral oxygen saturation(rSO2)in postoperative delirium(POD)in elderly patients undergoing radical resection of rectal cancer.Methods A total of 88 patients who underwent radical resection of rectal cancer in the Department of Anesthesiology,Gansu Provincial Hospital from August 2022 to February 2023 were observed.rSO2,heart rate(HR),mean arterial pressure(MAP),and blood oxygen saturation(SpO2)before anesthesia induction(T0),after tracheal intubation(T1),at the beginning of surgery(T2),at 1 h after the beginning of surgery(T3),at 2 h after the beginning of surgery(T4),and at the end of surgery(T5)were monitored after included.rSO2 at T0 was considered as the baseline value,to calculate the minimum value(rSO2min),mean value(rSO2mean),and maximum difference decreased from the baseline value(rSO2%max)of rSO2.After surgery,patients were divided into a POD group and a non-POD group based on the presence or absence of POD.HR,MAP,SpO2,and rSO2 were compared between the two groups.Results The HR,MAP,and SpO2 at T0,T1,T2,T3,T4,and T5,and rSO2 at T0,T1 and T2 between the POD group and the non-POD group were compared,without statistically significant differences(P>0.05).The rSO2 at T3,T4,and T5in the POD group were lower than those in the non-POD group,with statistically significant difference(P<0.05).The rSO2 baseline value was compared between the POD group and the non-POD group,without statistically significant difference(P>0.05).The rSO2 min and rSO2 mean in the POD group were lower than those in the non-POD group,while the rSO2%max in the POD group was higher than that in the non-POD group,with statistically significant differences(P<0.05).Conclusion The decrease in rSO2 is associated with POD in elderly patients undergoing radical resection of rectal cancer,and rSO2 can be used as a predictor of POD.

仇灵琴;葛莉;周海娇

甘肃省人民医院麻醉科,甘肃兰州 730000

临床医学

局部脑氧饱和度;老年;直肠癌根治术;谵妄

Regional cerebral oxygen saturation;Elderly;Radical resection of rectal cancer;Delirium

《中国医药科学》 2024 (006)

84-87 / 4

甘肃省自然科学基金支撑项目(22JR11RA260).

10.20116/j.issn2095-0616.2024.06.19

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