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木质纤维素生物转化的技术研究和应用前景OA

Technical research and application prospects of lignocellulose biotransformation

中文摘要英文摘要

随着工业化进程的发展,不可再生能源的消耗以及环境的污染问题是面临的严峻挑战.因此,可再生生物质资源的开发得到了广泛关注.木质纤维素是一种丰富的可再生生物质资源,可用于生物化学品和生物燃料的生产.然而,其复杂的结构阻碍了木质纤维素生物转化的最终效率.有效的预处理技术以及合适的转化宿主为木质纤维素的生物转化提供了帮助.此外,选择合适的木质纤维素转化工艺更有利于目标产物的合成,其中包括单独水解和发酵、同步糖化和发酵以及统合生物加工过程.在这些工艺中,通过统合生物加工过程构建的微生物共培养系统被认为是高效生产生物化学品和生物燃料的潜在策略.进一步,将共培养体系与合成生物学和代谢工程相结合,为未来构建高效稳定的木质纤维素生物转化体系提供了理论指导.

With the progress of industrialization,the consumption of non-renewable energy and the issue of environmental pollution have intensified.Consequently,the development of renewable biomass resources has gained significant attention.Lignocellulose,as an abundant renewable biomass resource,holds immense potential for the production of biofuels and biochemicals.However,its complex structure presents challenges to achieving optimal efficiency in lignocellulose biotransformation.Effective pre-treatment techniques and suitable transformation hosts contribute to facilitating the biotransformation of lignocellulose.Furthermore,the selection of appropriate lignocellulose conversion processes enhances the synthesis of desired products,including separate hydrolysis and fermentation,simultaneous sac-charification and fermentation,as well as consolidated bioprocessing.Among these approaches,the uti-lization of a microbe co-culture system,established through consolidated bioprocessing,is considered to be a promising strategy for efficiently producing biofuels and biochemicals.Additionally,the integra-tion of the co-culture system with synthetic biology and metabolic engineering offers theoretical guidance for constructing efficient and stable lignocellulose biotransformation systems in the future.

潘润泽;牟璐;邱敏;姜万奎;章文明;蒋羽佳;信丰学;姜岷

南京工业大学生物与制药工程学院材料化学工程国家重点实验室,江苏南京 211816南京工业大学生物与制药工程学院材料化学工程国家重点实验室,江苏南京 211816||南京工业大学江苏先进生物与化学制造协同创新中心(SICAM),江苏南京 211816

环境科学

木质纤维素;生物转化;糖化;发酵;统合生物加工过程

Lignocellulose;Biotransformation;Saccharification;Fermentation;Consolidated biopro-cessing

《能源环境保护》 2024 (002)

94-104 / 11

国家自然科学基金面上资助项目(22178169);江苏省杰出青年基金资助项目(BK20220052);山东省泰山产业领军人才工程资助项目(202306155)

10.20078/j.eep.20231203

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