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中医药治疗结直肠癌术后复发转移的相关作用机制研究进展OA

Research progress on the mechanism of action of traditional Chinese medicine in treating postoperative recurrence and metastasis of colorectal cancer

中文摘要英文摘要

临床上晚期结直肠癌患者术后发生复发和转移的现象十分常见,使得患者的生存质量低下、生存期缩短,是目前肿瘤学界研究的热点之一.中西医在治疗结直肠癌中各有优势,但二者联合起来可扬长避短,做到"1+1>2",可以明显改善患者临床症状,提高患者生存质量,并降低相应的复发转移率.为探究中医药在结直肠癌治疗中的相关作用机制,进一步提高中医药治疗晚期结直肠癌患者的疗效,本文通过查阅大量相关文献,对晚期结直肠癌术后发生复发转移的中医相关作用机制进行了以下总结:气虚、阳虚、蓄毒不流(痰湿、瘀血、气滞)、内生癌毒.

The phenomenon of postoperative recurrence and metastasis in patients with advanced colorectal cancer is very common in clinical practice,leading to low quality of life and shortened survival time.It is thus currently one of the hotspots in the field of oncology research.Traditional Chinese and Western medicine have their respective advantages in treating colorectal cancer,but when combined,they can enhance strengths and avoid weaknesses,achieving a"1+1>2"effect.It can significantly improve clinical symptoms,improve quality of life of patients,and reduce the corresponding recurrence and metastasis rate.To explore the relevant mechanisms of action of traditional Chinese medicine in the treatment of colorectal cancer and further improve the efficacy of traditional Chinese medicine in the treatment of patients with advanced colorectal cancer,this article summarizes the relevant mechanisms of action of traditional Chinese medicine in the recurrence and metastasis of advanced colorectal cancer after surgery by consulting a large number of relevant literature:qi deficiency,yang deficiency,retention of toxin(phlegm dampness,blood stasis,qi stagnation),and endogenous cancer toxin.

彭永焕;黄学宽;周德奇;唐睿;肖国航

重庆医科大学,重庆 400016重庆市北碚区中医院,重庆 400700广州中医药大学,广东广州 510006

中医学

中医药;晚期结直肠癌术后;复发转移;中医作用机制

Traditional Chinese medicine;Postoperative treatment for advanced colorectal cancer;Recurrent and metastasis;Mechanism of action of traditional Chinese medicine

《中国医药科学》 2024 (005)

50-53 / 4

10.20116/j.issn2095-0616.2024.05.11

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