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基于决策树模型的一次性胃肠镜的经济学评价OA

Economic Evaluation of Disposable Gastrointestinal Endoscope based on Decision Tree Model

中文摘要英文摘要

目的 系统评价使用 EndoFresh 一次性胃肠镜对比常规胃肠镜进行消化道疾病诊治的经济性,为政府决策、临床提供循证证据及对策建议.方法 建立决策树模型对EndoFresh一次性胃肠镜和常规复用胃肠镜进行成本-效果分析,效果参数和成本参数来源于文献和专家咨询,通过单因素敏感性分析对模型参数的不确定性进行分析,模拟的时间跨度为30 d.结果 普通患者中EndoFresh一次性胃肠镜治疗与常规复用胃肠镜治疗相比的增量成本-效果比(ICER)值为 304255.8,使用常规胃肠镜患者继发感染的风险对结果稳健性影响最大;易感患者中 EndoFresh 一次性胃肠镜治疗与常规复用胃肠镜治疗相比的ICER值为216613.7,使用常规胃肠镜患者继发感染的风险对结果稳健性影响最大.结论 以中国2021 年3 倍人均GDP作为阈值,在易感患者群体中EndoFresh一次性胃肠镜治疗比常规胃肠镜治疗更具有成本-效果.

Objective To systemically evaluate the economics of using EndoFresh disposable gastrointestinal endoscope compared to conventional gastrointestinal endoscopes for diagnosis and treatment of gastrointestinal diseases,and provide evidence-based recommendations to government and clinical decision-making.Methods A decision tree model was established for cost-effectiveness analysis between the EndoFresh disposable gastrointestinal endoscope and conventional reusable endoscope,with effectiveness parameters and cost parameters sourced from literature and expert consultation.The uncertainty of model parameters was analyzed by single-factor sensitivity analysis,and the simulated time span was 30 days.Results The incremental cost-effectiveness ratio(ICER)for EndoFresh single-use gastrointestinal endoscopy treatment compared to conventional reusable endoscopy treatment in the general patient population was 304255.8.The risk of secondary infection in patients undergoing conventional endoscopy had the greatest impact on the robustness of the results.In susceptible patients,the ICER for EndoFresh single-use gastrointestinal endoscopy treatment compared to conventional reusable endoscopy treatment was 216613.7,with the risk of secondary infection in patients undergoing conventional endoscopy having the greatest impact on the robustness of the results.Conclusion Taking 3 times China's GDP per capita in 2021 as the threshold,EndoFresh one-time gastroenteroscopy is more cost-effective than conventional gastroenteroscopy in susceptible patient groups.

朱致旭;孙辉;严俊涛;李福明;彭宇欣;陈英耀;魏艳

复旦大学公共卫生学院,上海 200032||国家卫生健康委员会卫生技术评估重点实验室(复旦大学),上海 200032复旦大学公共卫生学院,上海 200032||国家卫生健康委员会卫生技术评估重点实验室(复旦大学),上海 200032||上海市卫生和健康发展研究中心,上海 201199

临床医学

一次性胃肠镜;决策树模型;成本-效果分析

Disposable gastrointestinal endoscope;Decision tree model;Cost-Effectiveness analysis

《中国药物经济学》 2024 (002)

21-25 / 5

10.12010/j.issn.1673-5846.2024.02.004

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