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江苏省农村惊厥性癫痫患者治疗缺口分析OACSTPCD

Analysis of treatment gap of convulsive epilepsy patients in rural areas of Jiangsu Province

中文摘要英文摘要

目的 探讨江苏省农村地区惊厥性癫痫的治疗缺口以及影响因素.方法 对 2005-2020 年筛查的7836 例农村惊厥性癫痫患者的临床资料进行统计,分析癫痫患者的治疗现状、治疗缺口以及相关的影响因素.结果 本研究共入组 7 836 例惊厥性癫痫患者.江苏省农村地区惊厥性癫痫的治疗缺口为69.05%.不同性别间的治疗缺口差异无统计学意义(P>0.05);不同年龄段(χ2 =12.196,P =0.007)、不同首发年龄患者(χ2 =58.658,P<0.001)、不同病程(χ2 =65.430,P<0.001)、不同发作次数(χ2 =171.276,P<0.001)、不同就诊医院级别(χ2 =122.076,P<0.001)的治疗缺口差异有统计学意义.多因素Logistic回归分析显示,首发年龄越大、病程越短、发作越频繁,癫痫患者的治疗缺口越大(均P<0.05).在患病年龄和就诊医院上,45~59 岁(P =0.012)以及就诊于市县级医院(P<0.001)的患者更倾向于接受正规抗癫痫治疗.结论 江苏省农村地区惊厥性癫痫患者的治疗缺口较大.主要原因可能是对癫痫的认识不足以及基层医院建设滞后.

Objective To explore the treatment gap and influencing factors of convulsive epilepsy in rural areas of Jiangsu Province.Methods The clinical data of 7836 rural convulsive epilepsy patients screened from 2005 to 2020 were statistically analyzed,and the treatment status,treatment gap and related influencing factors of epilepsy patients were analyzed.Results A total of 7836 patients with convulsive epilepsy were enrolled in this study.The treatment gap for convulsive epilepsy in rural areas of Jiangsu Province was 69.05%.There was no significant difference in the treatment gap between different genders(P>0.05).There were statistically significant differences in the treatment gap between age(χ2 = 12.196,P =0.007),age of onset(χ2 =58.658,P<0.001),disease duration(χ2 =65.430,P<0.001),seizure frequency(χ2 =171.276,P<0.001),and hospitalization level(χ2 = 122.076,P<0.001).Multivariate Logistic regression analysis showed that the older the age of onset was,the shorter the course of the disease was,the more frequent the seizures was,and the greater the treatment gap in patients with epilepsy was(all P<0.05).Patients aged 45-59 years(P =0.012)and treated in municipal and county hospitals(P<0.001)were more likely to receive regular anti-epileptic treatment.Conclusions There is a significant treatment gap for convulsive epilepsy patients in rural areas of Jiangsu Province.This may be due to insufficient awareness of epilepsy and the underdevelopment of primary healthcare institutions.

孙方玲;余传勇;李炎章;李亦涵;王英藩;王思懿;许峰源;王小姗

210029 南京医科大学附属脑科医院神经内科

临床医学

惊厥性癫痫;农村地区;治疗缺口;现状调查

convulsive epilepsy;rural areas;treatment gap;investigation of current situation

《临床神经病学杂志》 2024 (001)

20-25 / 6

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