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肌少症对帕金森病患者平衡功能的影响OA

Effect of sarcopenia on balance function in patients with Parkinson's disease

中文摘要英文摘要

目的 探讨肌少症对帕金森病(Parkinson's disease,PD)患者平衡功能的影响.方法 选取 2021 年 01 月-2021 年06 月经过温州市中心医院确诊为PD患者 60 例作为研究对象,根据 2014 年亚洲肌肉减少症工作小组(Asian Working Group for Sarcopenia,AWGS)制定的诊断标准将所有患者分为肌少症组和对照组.比较两组UPDRS Ⅲ、Berg平衡量表、计时起立-行走测试(timed-up-go test,TUG)、活动平衡信心量表.结果 与对照组比较,肌少症组握力、步速、RASM上更低(P<0.05);跌倒次数、UPDRS Ⅲ、Berg评分、TUG时长均显著增加(P<0.05).肌少症组在活动平衡信心量表(activities-specific balance confidence scale,ABC)总分、ABC-2、ABC-3、ABC-5、ABC-6、ABC-7、ABC-8、ABC-9、ABC-11、ABC-14、ABC-15、ABC-16 表现较差,差异均有统计学意义(P<0.05).进一步分析不同性别之间差异,本研究发现女性肌少症患者 ABC-2、ABC-3、ABC-8、ABC-9、ABC-11、ABC-13、ABC-14、ABC-15、ABC-16、总分指标得分更低,差异有统计学意义(P<0.05).结论 肌少症对PD平衡功能影响明显,增加患者跌倒风险.

Objective To investigate the effect of sarcopenia on balance function in patients with Parkinson's disease(PD).Methods Sixty patients with PD diagnosed by our hospital from January 2021 to June 2021 were selected as the study objects.All patients were divided into myopenia group and control group according to the diagnostic criteria established by the Asian Working Group for Sarcopenia(AWGS)in 2014.The UPDRS Ⅲ,Berg balance scale,timed-up-go test and activity balance confidence scale were compared between the two groups.Results The grip strength,walking speed and RASM of the myopenia group were lower than those of the control group(P<0.05);Compared with the control group,the number of falls,UPDRS Ⅲ,Berg score and TUG duration in the myopenia group were significantly increased(P<0.05).The total score of ABC,ABC-2,ABC-3,ABC-5,ABC-6,ABC-7,ABC-8,ABC-9,ABC-11,ABC-14,ABC-15,ABC-16 in myopenia group were poor,and the differences were statistically significant(P<0.05).Further analyzing the differences between sex genders,we found that female sarcopenia had lower scores on ABC-2,ABC-3,ABC-8,ABC-9,ABC-11,ABC-13,ABC-14,ABC-15,ABC-16,and total score indexes,with statistically significant differences.Conclusion Myopenia significantly affects the balance function of PD and increases the risk of falls.

张雅西;林彩丹;金海敏;黄向东

温州市中心医院神经内科,浙江温州 325000

临床医学

帕金森病;肌少症;平衡功能

Parkinson's disease;Myopenia;Balance function

《中国现代医生》 2024 (002)

29-32 / 4

浙江省医学会临床科研基金项目(2021ZYC-B04);温州市基础性科研项目(Y2020428)

10.3969/j.issn.1673-9701.2024.02.007

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