针刺相关技术防治术后恶心呕吐的机制研究OACSTPCD

Acupuncture related techniques have a definite therapeutic effect on the prevention and treatment of postoperative nausea and vomiting(PONV),which can reduce the incidence of adverse events.This may mainly be achieved by stimulating sympathetic and par-asympathetic nerve activity,regulating 5-HT and β-endorphin,the levels of neurotransmitters such as endorphins regulate gastrointes-tinal motility and nerve conduction.At present,relevant studies mainly focus on acupoints Neiguan and Zusanli,and the specificity of acupoints may be related to their distribution,tissue composition,and nerve innervation.Whether the laterality of acupoints affects the therapeutic effect remains to be explored.Different frequencies of electrical stimulation can produce the release of different chemical neurotransmitters,and there is a lack of systematic comparative research on which frequency can achieve the best prevention and control effect.At present,most of the relevant research is clinical trials,lacking unified and standardized standards.It is urgent to standardize the principles of acupoint selection and intervention timing,and further explore their mechanisms of action on this basis.In addition,it is necessary to further strengthen multicenter research on the prevention and treatment of PONV with electroacupuncture,explore its mech-anism of action,and provide more theoretical basis for the application of acupuncture related techniques in the perioperative period.