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基于"三焦命门"学说探讨肾癌发生、转移的病机及临床证治OACSTPCD

Pathogenesis and Clinical Treatment of Renal Cancer and Metastasis Based on Theory of"Sanjiao and Mingmen"

中文摘要英文摘要

肾癌发生本于命门虚衰、肾元不足致三焦气机不利,久则内生痰湿瘀血,为本虚标实之证.肾癌肺转移的病机为肺阴两虚,三焦阻滞致使痰饮之邪凝聚于肺金,发为肺积;肾主骨生髓,肾癌本为肾元亏损、肾阴阳两虚,藏于命门之肾精不足,不能充养骨骼,骨骼失养易被癌毒邪气侵袭发为骨枯;脑为髓海,肾虚髓海失养,痰瘀易上扰清窍,阻滞脑络血运,从而出现脑部转移;三焦主淋巴腺,三焦不畅痰瘀凝聚成核则表现为周身淋巴结肿大.临证治疗肾癌的转移当以温补命门、培元固本为根本之法,兼以疏利三焦气机、祛瘀化痰、解毒散结应对转移之症,同时强调补益脾胃,脾胃强健则化源不竭,以达到补后天充养先天之目的.

Renal cancer occurs due to the deficiency of the Mingmen and the deficiency of the Kidney element,which leads to the disad-vantageous Qi mechanism of the Sanjiao.Over time,there is endogenous Phlegm Dampness and blood stasis,which is a syndrome of de-ficiency in root and excess in symptom.The pathogenesis of lung metastasis in renal cell carcinoma is the deficiency of Lung Yin and Yang,and the obstruction of the Sanjiao,which leads to the accumulation of Phlegm in the Lung,resulting in Lung accumulation.Kidney governs bone and generates marrow.Renal cancer is originally caused by a deficiency of Kidney Yuan Qi as well as deficiency of Kidney yin and yang.The Kidney Essence hidden in the Mingmen is insufficient,which cannot nourish the bones.If the bones lose nourish-ment,they are easily invaded by cancer Toxin and other Evil factors,leading to bone necrosis.The brain is a sea of marrow,and due to Kidney deficiency,the sea of marrow loses nourishment.Phlegm and blood stasis can easily disturb the clear orifices,block the blood flow of the brain meridians,and thus lead to brain metastasis.The main lymph nodes of the Sanjiao are enlarged lymph nodes around the body if the Sanjiao is not smooth and Phlegm stasis condenses into lymphadenopathy.The clinical treatment of renal cancer metastasis should be based on the fundamental method of warming and tonifying the Mingmen,strengthening the foundation,and treating the symp-toms of metastasis with the methods of regulating the Qi mechanism of Sanjiao,removing blood stasis and Phlegm as well as detoxifying and dispersing nodules.At the same time,emphasis should be placed on tonifying the Spleen and Stomach.If the Spleen and Stomach are strong,the source of Yuan Qi will not be exhausted an can achieve the goal of nourishing the acquired and in turn nourishing the in-nate.

石智尧;孙启蒙;高宇;尹艺杰;刘佳佳;王晞星

山西中医药大学,山西 太原 030024山西省中医药研究院,山西 太原 030012

中医学

肾癌;肾癌肺转移;肾癌骨转移;肾癌脑转移;肾癌淋巴转移;"三焦命门"学说

renal cancer;renal cancer lung metastasis;renal cancer bone metastasis;renal cancer brain metastasis;renal cancer lymph metastasis;"Sanjiao and Mingmen"theory

《中医学报》 2024 (001)

34-38 / 5

第四届国医大师传承工作室项目{国中医药办人教函[2022]245号};国家中医药传承创新中心建设项目(202203);山西省中医临床医学研究中心(培育)项目{晋科社发[2019]61号};山西省医学科技创新团队项目(2020TD04);山西省医学重大科技攻关项目(2022XM10)

10.16368/j.issn.1674-8999.2024.01.007

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