目的 分析中医药联合经导管动脉化疗栓塞(transcatheter arterial chemoembolization,TACE)治疗肝癌研究领域的现状、热点及趋势.方法 检索中国知网 1994 年 1 月至 2022 年 12 月收录的有关中医药联合TACE治疗肝癌的相关文献,利用CiteSpace 6.1.R6 软件分析其发文量、作者、研究机构及关键词.结果 本研究共纳入 686 篇文献,1994-2015年发文量呈现波动上升趋势,但自 2016 开始发文量有所下降,证明该领域还需要进一步突破性研究.发文作者及研究机构彼此之间的交流有待加强,跨机构、跨区域合作度较低,地域分布不均,应加强合作.高频关键词有肝癌、中药、介入治疗、治疗性等,得到 9 个关键词聚类标签.结论 目前中医药联合TACE 治疗肝癌较缺乏实验研究及相关机制的研究,未来的研究热点将更多地聚焦在中医药、介入治疗、临床观察及细胞凋亡方面,为今后开展相关研究的科研人员提供新的思路.
Objective To analyze the current status,hotspots,and trends in the research field of traditional Chinese medicine and pharmacy combined with transcatheter arterial chemoembolization(TACE)for the treatment of hepatocellular carcinoma.Methods The relevant literatures on traditional Chinese medicine and pharmacy combined with TACE treatment for hepatocellular carcinoma collected by China National Knowledge Infrastructure from January 1994 to December 2022,and use CiteSpace 6.1.R6 software to analyze its publication volume,authors,research institutions,and key words.Results This study included a total of 686 articles.The publication volume showed a fluctuating upward trend from 1994 to 2015,but it had decreased since 2016,indicating that further breakthrough research was needed in this field.The communication between authors and research institutions needed to be strengthened,with low levels of cross institutional and cross regional cooperation and uneven geographical distribution.Cooperation should be strengthened.High frequency key words included hepatocellular carcinoma,Chinese materia medica,interventional therapy,therapeutic,etc.,resulting in 9 key word clustering labels.Conclusion Currently,there is a lack of experimental research and related mechanism research,the future research hotspots of traditional Chinese medicine and pharmacy combined with TACE treatment for hepatocellular carcinoma will focus more on traditional Chinese medicine and pharmacy,interventional therapy,clinical observation,and cell apoptosis,which provides new ideas for researchers conducting related research in the future.
刘子铭;戴铭;黄晶晶;吕建林;张文富
广西中医药大学研究生院,广西南宁 530200广西中医药大学研究生院,广西南宁 530200||广西中医基础研究重点实验室,广西南宁 530200广西中医药大学第一附属医院脾胃肝病科,广西南宁 530023||广西高发传染病中西医结合转化医学重点实验室,广西南宁 530200
中医学
肝癌;中医药;经导管动脉化疗栓塞;可视化分析
Hepatocellular carcinoma;Traditional Chinese medicine and pharmacy;Transcatheter arterial chemoembolization;Visualization analysis
《中国现代医生》 2024 (001)
1-6 / 6
国家自然科学基金项目(81760845,81860839);广西名中医工作室建设项目(2023017-05-09)
10.3969/j.issn.1673-9701.2024.01.001
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