树状大分子是一类高度支化的单分散性大分子,具有精确可控的分子结构.本文在树状大分子结构特点的基础上,阐述了以树状大分子为载体的新型纳米CT成像造影剂的合成及其在CT成像中的应用,并对树状大分子在CT成像中的发展趋势和应用领域进行了展望.
Dendrimers are a family of highly branched, monodispersed synthetic macromolecules with well defined structural composition and architecture. Based on the unique structure of dendrimers, the synthesis and application of novel types of dendrimer-related CT imaging agents are reviewed in this article. Furthermore, future perspectives in the application and development of dendrimers-based CT imaging contrast agents are introduced.
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