目的 比较Gd-EOB-DTPA增强磁共振成像(MRI)容积动态多时相扫描(LAVA)与MR扩散加权成像(DWI)扫描对肝转移瘤(≤3 cm)的检出价值.方法 回顾性分析16例肝转移瘤患者的MR资料,所用序列包括T1WI、T2WI,3D-LAVA增强MRI和b值为500s/mm2的DWI.将所有患者分成2组并进行比较:A组(T1WI、T2WI和LAVA增强MRI),B组(T1WI、T2WI和DWI).对于所有肝转移灶,采用受试者工作特征曲线(ROC)分析每组检查的诊断价值.结果 共确定39个肝转移灶,A组的敏感性、特异性、Youden指数和ROC曲线下面积(AUC)分别为97.4％、88.2％、0.856和0.944,B组分别为82.1％、91.2％、0.733和0.834,其中,A组的AUC(P=0.040)和Youden指数(P=0.043)均明显大于B组.结论 Gd-EOB-DTPA增强MRI在检出小转移灶方面较DWI准确性更高.
Objective To compare the roles of Gd-EOB-DTPA-enhanced magnetic resonance imaging (MRI) using the liver acquisition with volume acceleration (LAVA) sequence and diffusion-weighted imaging (DWI) in the detection of hepatic metastases sized ≤3 cm. Methods We retrospectively analyzed the MRI data of 16 patients with hepatic metastases. All the sequences used included T1WI, T2WI, 3D-LAVA, and DWI (b value = 500 s/mm2). All patients were divided into two groups based on the sequences ; group A (T1WI, T2WI, and 3D-LAVA enhanced MR) and group B (T1WI, T2WIandDWI). The hepatic metastases were evaluated by analyzing the receiver operating characteristic (ROC) curves. Results A total of 39 hepatic metastatic lesions were identified. The sensitivity, specificity, Youden index and the area under the ROC curve ( AUC) were 97. 4% , 88. 2% , 0. 856, and 0. 944 in group A and 82. 1% , 91. 2% , 0. 733 , and 0. 834 in group B. The ROC curves (P= 0.040) and Youden index (P=0.043) in group A were significantly larger than in group B. Conclusion Gadolinium-EOB-DTPA-enhanced MRI has higher accuracy than DWI in the detection of small metastases.
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